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KMID : 0360220110520070771
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Journal of the Korean Ophthalmological Society
2011 Volume.52 No. 7 p.771 ~ p.776
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Risk Factors for Dry Eye in Thyroid-Associated Ophthalmopathy
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Kim Jae-Ryun
Yim Hye-Bin
Chung Sung-Kun
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Abstract
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Purpose:To investigate the risk factors for dry eye in thyroid-associated ophthalmopathy patients.
Methods:The present retrospective study was conducted on 78 eyes in 39 patients diagnosed with thyroid-associated ophthalmopathy. The risk factors for dry eye in thyroid-associated ophthalmopathy patients were examined by analyzing data including tear break-up time, Schirmer’s test, age, gender, thyroid function status, palpebral fissure width, lagophthalmos, eyelid retraction, and exophthalmos through multiple logistic regression analysis.
Results:The risk factors for dry eye disease were palpebral fissure width (OR = 3.422, p = 0.022) and lagophthalmos (OR = 13.068, p = 0.049). Age, gender, thyroid hormone status, eyelid retraction and exophthalmos did not show significant association with dry eye in multiple logistic regression analysis. The only risk factor for tear film break-up time less than 10 seconds was palpebral fissure width (OR = 2.787, p = 0.045), and none of the risk factors for Schirmer’s test less than 10 mm at 5 minutes were statistically significant.
Conclusions:Risk factors for dry eye in thyroid ophthalmopathy patients were palpebral fissure width and lagophthalmos. J Korean Ophthalmol Soc 2011;52(7):771-776
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KEYWORD
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Dry eye syndrome, Risk factors, Thyroid-associated ophthalmopathy
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